Thứ Sáu, 26 tháng 5, 2017

A new lupane triterpene from Tetracera scandens L., xanthine oxidase inhibitor

From the MeOH extract of the stem ofTetracera scandensL., a newnor-lupane triterpene, 28-O-�-D-glucopyranosyl ester of platanic acid (1), has been isolated together with six known compounds. Their structures were elucidated on the basis of spectroscopic data. Compounds1–6displayed significant xanthine oxidase inhibitory activity in a concentration-dependent manner, and compound 4 showed more potent inhibitory activity with an IC50value of 1.9mM than that of a positive control allopurinol (IC502.5mM)

http://repository.vnu.edu.vn/handle/VNU_123/33043

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